- Symbol
- SNF1
- Aliases
- CAT1; CCR1; GLC2; HAF3; PAS14
- Name
- AMP-activated serine/threonine protein kinase
- Organism
- Saccharomyces cerevisiae (AnAge)
- Observations
- Overexpression shortened lifespan accompanied by signs of premature ageing.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Overexpression
- Longevity Category
- Anti-Longevity
- Primary reference
-
- Observations
- Replicative lifespan increased by 50% in the alpha strain
- % change in avg or median lifespan
- Replicative lifespan is 50% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Deletion
- Longevity Category
- Anti-Longevity
- Primary reference
-
- Observations
- Reduced chronological lifespan
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Overexpression
- Longevity Category
- Anti-Longevity
- Primary reference
-
- Observations
- Mean chronological lifespan decreased in the a strain
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Deletion
- Longevity Category
- Necessary for fitness
- Primary reference
-
- GenAge model organism genes
- A homolog of this gene for Caenorhabditis elegans is present as aak-2
- A homolog of this gene for Drosophila melanogaster is present as SNF1A
- GenDR gene manipulations
- A homolog of this gene for Caenorhabditis elegans is present as aak-2
- LongevityMap
- A homolog of this gene for Homo sapiens is present as PRKAA1
- CellAge
- A homolog of this gene for Homo sapiens is present as NUAK1
- A homolog of this gene for Homo sapiens is present as NUAK2
- A homolog of this gene for Homo sapiens is present as PRKAA2
- A homolog of this gene for Homo sapiens is present as SIK1
- CellAge gene expression
- A homolog of this gene for Homo sapiens is present as NUAK1
- Caenorhabditis elegans
- par-1
- Caenorhabditis elegans
- kin-29
- Caenorhabditis elegans
- aak-2
- Caenorhabditis elegans
- unc-82
- Caenorhabditis elegans
- aak-1
- Danio rerio
- MARK4 (1 of many)
- Danio rerio
- nuak1b
- Danio rerio
- prkaa1
- Danio rerio
- mark3b
- Danio rerio
- mark4a
- Danio rerio
- sik2b
- Danio rerio
- zgc:66101
- Danio rerio
- mark3a
- Danio rerio
- sik1
- Danio rerio
- nuak2
- Danio rerio
- si:ch211-117c9.1
- Danio rerio
- prkaa2
- Danio rerio
- mark2a
- Danio rerio
- nuak1a
- Danio rerio
- MARK1
- Danio rerio
- sik2a
- Danio rerio
- mark2b
- Drosophila melanogaster
- KP78a
- Drosophila melanogaster
- KP78b
- Drosophila melanogaster
- CG43143
- Drosophila melanogaster
- Sik2
- Drosophila melanogaster
- AMPKalpha
- Drosophila melanogaster
- Sik3
- Drosophila melanogaster
- par-1
- Homo sapiens
- PRKAA1
- Homo sapiens
- PRKAA2
- Homo sapiens
- NUAK1
- Homo sapiens
- SIK2
- Homo sapiens
- SIK3
- Homo sapiens
- MARK3
- Homo sapiens
- MARK1
- Homo sapiens
- 102724428
- Homo sapiens
- SIK1
- Homo sapiens
- MARK4
- Homo sapiens
- NUAK2
- Homo sapiens
- MARK2
- Mus musculus
- Mark2
- Mus musculus
- Mark3
- Mus musculus
- Sik2
- Mus musculus
- Sik3
- Mus musculus
- Nuak1
- Mus musculus
- Prkaa1
- Mus musculus
- Mark1
- Mus musculus
- Mark4
- Mus musculus
- Nuak2
- Mus musculus
- Prkaa2
- Mus musculus
- Sik1
- Rattus norvegicus
- Mark3
- Rattus norvegicus
- Prkaa2
- Rattus norvegicus
- Prkaa1
- Rattus norvegicus
- Mark2
- Rattus norvegicus
- Sik1
- Rattus norvegicus
- Mark1
- Rattus norvegicus
- Sik2
- Rattus norvegicus
- Sik3
- Rattus norvegicus
- Mark4
- Rattus norvegicus
- Nuak1
- Rattus norvegicus
- Nuak2
- Schizosaccharomyces pombe
- ssp2
- Saccharomyces Genome Database
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (852088)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar