Cell Senescence Entries for NUAK2
- Cell Types
- Melanoma
- Cell Lines
- C32
- Cancer Cell?
- Yes
- Method
- Knockdown
- Type of senescence
- Oncogene-induced
- Senescence Effect
- Inhibits
- Primary Reference
- Namiki et al. (2011) AMP kinase-related kinase NUAK2 affects tumor growth, migration, and clinical outcome of human melanoma. Proc Natl Acad Sci U S A 108(16)6597-602 (PubMed)
NUAK2 Gene Information
- HGNC symbol
- NUAK2
- Aliases
- FLJ90349; SNARK
- Common name
- NUAK family kinase 2
- Entrez Id
- 81788
- Description
NUAK2 Ontologies
- Gene Ontology
-
Process: GO:6468; protein phosphorylation
GO:16310; phosphorylation
GO:43066; negative regulation of apoptotic process
GO:30036; actin cytoskeleton organization
GO:6915; apoptotic process
GO:35556; intracellular signal transduction
GO:42149; cellular response to glucose starvation
Cellular component: GO:5737; cytoplasm
Function: GO:46872; metal ion binding
GO:166; nucleotide binding
GO:4672; protein kinase activity
GO:4674; protein serine/threonine kinase activity
GO:4712; protein serine/threonine/tyrosine kinase activity
GO:5524; ATP binding
GO:16301; kinase activity
GO:16740; transferase activity
GO:106310; protein serine kinase activity
GO:5515; protein binding
GO:287; magnesium ion binding
And 1 more GO terms
Homologs of NUAK2 in Model Organisms
- Caenorhabditis elegans
- unc-82
- Danio rerio
- nuak2
- Drosophila melanogaster
- CG43143
- Mus musculus
- Nuak2
- Rattus norvegicus
- Nuak2
- Saccharomyces cerevisiae
- SNF1
In other databases
- GenAge model organism genes
- A homolog of this gene for Saccharomyces cerevisiae is present as SNF1
External links
- OMIM
- 608131
- Ensembl
- ENSG00000163545
- Entrez Gene
- 81788
- UniGene
- 497512
- 1000 Genomes
- 1000 Genomes
- HPRD
- GenAtlas
- NUAK2
- GeneCards
- NUAK2