Mus musculusGenAge entry for Slc13a1 (Mus musculus)

Gene information (ID: 825)

Symbol
Slc13a1
Aliases
Nas1; NaSi-1; AI314066; AI987826
Name
Solute carrier family 13 (sodium/sulfate symporters), member 1
Organism
Mus musculus (AnAge)

Potential relevance to longevity and/or ageing

Observations
Hyposulfataemic NaS1 null (Nas1 -/- ) mice were found to live longer and have less tumors in aged mice. Median lifespans increased in both male and female Nas1- /- mice when compared with Nas1+/+ mice.
% change in max lifespan
Maximum lifespan is aprox. 25% higher for males only.
% change in avg or median lifespan
Median lifespan is approximately 25% higher for both sexes.
Lifespan Effect
Increase
Genetic Manipulation
Deletion
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Drosophila melanogaster is present as Indy
    • A homolog of this gene for Caenorhabditis elegans is present as nac-3
    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as SLC13A1
    GenDR gene manipulations
    • A homolog of this gene for Drosophila melanogaster is present as Indy

    Homologs in other organisms

    Caenorhabditis elegans
    nac-1
    Caenorhabditis elegans
    nac-3
    Danio rerio
    slc13a1
    Drosophila melanogaster
    CG33934
    Drosophila melanogaster
    Indy-2
    Drosophila melanogaster
    CG7309
    Drosophila melanogaster
    Indy
    Homo sapiens
    SLC13A1
    Rattus norvegicus
    Slc13a1

    External links

    Mouse Genome Informatics
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (55961)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar