GenAge entry for Sod2 (Mus musculus)
Gene information (ID: 827)
- Symbol
- Sod2
- Aliases
- MnSOD; Sod-2
- Name
- Superoxide dismutase 2, mitochondrial
- Organism
- Mus musculus (AnAge)
Potential relevance to longevity and/or ageing
- Observations
- Gene deletion in connective tissue resulted in mutant mice with a reduced lifespan and premature onset of aging-related phenotypes such as weight loss, skin atrophy, kyphosis, osteoporosis and muscle degeneration.
- % change in max lifespan
- Maximum lifespan is 14% lower.
- % change in avg or median lifespan
- Median lifespan is 43% lower.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Deletion in connective tissue
- Longevity Category
- Pro-Longevity
- Primary reference
-
In other databases
- GenAge model organism genes
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as SOD2
- GenDR gene manipulations
- A homolog of this gene for Saccharomyces cerevisiae is present as SOD2
- LongevityMap
- A homolog of this gene for Homo sapiens is present as SOD2
- CellAge
- A homolog of this gene for Homo sapiens is present as SOD2
Homologs in other organisms
- Caenorhabditis elegans
- sod-3
- Caenorhabditis elegans
- sod-2
- Danio rerio
- sod2
- Drosophila melanogaster
- Sod2
- Homo sapiens
- SOD2
- Homo sapiens
- SOD2
- Rattus norvegicus
- Sod2
- Saccharomyces cerevisiae
- SOD2
- Schizosaccharomyces pombe
- SPBC16A3.14
External links
- Mouse Genome Informatics
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (20656)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar