- Symbol
- SOD2
- Name
- Manganese-containing superoxide dismutase
- Organism
- Saccharomyces cerevisiae (AnAge)
- Known functions and activities
- Protects cells against oxygen toxicity
- Observations
- Overexpression of Sod1 and Sod2 extends survival by 30%.
- % change in avg or median lifespan
- Lifespan is 30% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression
- Longevity Category
- Pro-Longevity
- Primary reference
-
- Observations
- 72% replicative lifespan decrease
- % change in avg or median lifespan
- Replicative lifespan is 72% lower.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Deletion
- Longevity Category
- Necessary for fitness
- Primary reference
-
- Observations
- Mean chronological lifespan decreased in the a strain by more than 50%
- % change in avg or median lifespan
- Mean chronological lifespan is more than 50% lower.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Deletion
- Longevity Category
- Necessary for fitness
- Primary reference
-
- GenAge model organism genes
- A homolog of this gene for Drosophila melanogaster is present as Sod2
- A homolog of this gene for Mus musculus is present as Sod2
- A homolog of this gene for Caenorhabditis elegans is present as sod-2
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as SOD2
- GenDR gene manipulations
- This gene is present as SOD2
- LongevityMap
- A homolog of this gene for Homo sapiens is present as SOD2
- CellAge
- A homolog of this gene for Homo sapiens is present as SOD2
- Caenorhabditis elegans
- sod-2
- Caenorhabditis elegans
- sod-3
- Danio rerio
- sod2
- Drosophila melanogaster
- Sod2
- Homo sapiens
- SOD2
- Homo sapiens
- SOD2
- Mus musculus
- Sod2
- Rattus norvegicus
- Sod2
- Saccharomyces Genome Database
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (856399)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for SOD2 (Saccharomyces cerevisiae)