- Symbol
- Sod2
- Aliases
- CG8905; Dmel\CG8905; dSOD2; Mito; SOD; mitSOD2; Mn; SOD; M
- Name
- Superoxide dismutase 2 (Mn)
- Organism
- Drosophila melanogaster (AnAge)
- Known functions and activities
- Protects cells against oxygen toxicity
- Observations
- RNA interference results in increased oxidative stress and early-onset mortality in young adults.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- RNA interference
- Longevity Category
- Pro-Longevity
- Primary reference
-
- Observations
- Gene overexpression resulted in a 20% increase in mean and maximal lifespan.
- % change in max lifespan
- Maximum lifespan is 20% higher.
- % change in avg or median lifespan
- Average lifespan is 20% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression
- Longevity Category
- Pro-Longevity
- Primary reference
-
- GenAge model organism genes
- A homolog of this gene for Saccharomyces cerevisiae is present as SOD2
- A homolog of this gene for Mus musculus is present as Sod2
- A homolog of this gene for Caenorhabditis elegans is present as sod-2
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as SOD2
- GenDR gene manipulations
- A homolog of this gene for Saccharomyces cerevisiae is present as SOD2
- LongevityMap
- A homolog of this gene for Homo sapiens is present as SOD2
- CellAge
- A homolog of this gene for Homo sapiens is present as SOD2
- Caenorhabditis elegans
- sod-3
- Caenorhabditis elegans
- sod-2
- Danio rerio
- sod2
- Homo sapiens
- SOD2
- Homo sapiens
- SOD2
- Mus musculus
- Sod2
- Rattus norvegicus
- Sod2
- Saccharomyces cerevisiae
- SOD2
- Schizosaccharomyces pombe
- SPBC16A3.14
- FlyBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (36878)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar