- Symbol
- Mtor
- Aliases
- FRAP; flat; FRAP2; Frap1; RAFT1; RAPT1; AI327068; 2610315
- Name
- mechanistic target of rapamycin (serine/threonine kinase)
- Organism
- Mus musculus (AnAge)
- Observations
- Mice hypomorphic for mTor have reduced mTor expression, are smaller and live about 20% longer.
- % change in avg or median lifespan
- Average lifespan is 20% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Genetic reduction
- Longevity Category
- Anti-Longevity
- Primary reference
-
- GenAge model organism genes
- A homolog of this gene for Drosophila melanogaster is present as Tor
- A homolog of this gene for Saccharomyces cerevisiae is present as TOR1
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as MTOR
- GenDR gene manipulations
- A homolog of this gene for Saccharomyces cerevisiae is present as TOR1
- LongevityMap
- A homolog of this gene for Homo sapiens is present as MTOR
- CellAge
- A homolog of this gene for Homo sapiens is present as MTOR
- Danio rerio
- mtor
- Drosophila melanogaster
- Tor
- Homo sapiens
- MTOR
- Rattus norvegicus
- Mtor
- Saccharomyces cerevisiae
- TOR1
- Schizosaccharomyces pombe
- tor2
- Mouse Genome Informatics
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (56717)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar