Mus musculusGenAge entry for Mtor (Mus musculus)

Gene information (ID: 1809)

Symbol
Mtor
Aliases
FRAP; flat; FRAP2; Frap1; RAFT1; RAPT1; AI327068; 2610315
Name
mechanistic target of rapamycin (serine/threonine kinase)
Organism
Mus musculus (AnAge)

Potential relevance to longevity and/or ageing

Observations
Mice hypomorphic for mTor have reduced mTor expression, are smaller and live about 20% longer.
% change in avg or median lifespan
Average lifespan is 20% higher.
Lifespan Effect
Increase
Genetic Manipulation
Genetic reduction
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Drosophila melanogaster is present as Tor
    • A homolog of this gene for Saccharomyces cerevisiae is present as TOR1
    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as MTOR
    GenDR gene manipulations
    • A homolog of this gene for Saccharomyces cerevisiae is present as TOR1
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as MTOR
    CellAge
    • A homolog of this gene for Homo sapiens is present as MTOR

    Homologs in other organisms

    Danio rerio
    mtor
    Drosophila melanogaster
    Tor
    Homo sapiens
    MTOR
    Rattus norvegicus
    Mtor
    Saccharomyces cerevisiae
    TOR1
    Schizosaccharomyces pombe
    tor2

    External links

    Mouse Genome Informatics
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (56717)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar