GenDR Dietary Restriction Gene Manipulation: TOR1
Gene Information (Entrez Gene ID: 853529)
- Symbol
- TOR1
- Aliases
- DRR1
- Name
- Target Of Rapamycin 1
- Organism
- Saccharomyces cerevisiae (AnAge)
- Entrez Gene ID
- 853529
Potential relevance to dietary restriction and ageing
- Observations
-
TOR1 deletion extends mean and maximum replicative lifespan by 21 and 25% [1570] as well as chronological lifespan [2591]. This lifespan extension is independent of SIR2 [1570]. Deletion of TOR1 extends replicative lifespan as well as chronological lifespan [2591] and glucose restriction fails to further extend the long replicative lifespan of tor1Delta [1570] [2238] [2556]. Water starvation (extreme DR) further extends chronological lifespan of tor1 mutants [2556].
- References
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In other databases
- GenAge model organism genes
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as MTOR
- GenDR gene manipulations
- A homolog of this gene for Caenorhabditis elegans is present as let-363
- LongevityMap
- A homolog of this gene for Homo sapiens is present as MTOR
- CellAge
Homologs
- Caenorhabditis elegans
- let-363
- Caenorhabditis elegans
- smg-1
- Danio rerio
- smg1
- Danio rerio
- mtor
- Drosophila melanogaster
- Tor
- Drosophila melanogaster
- nonC
- Homo sapiens
- SMG1
- Homo sapiens
- MTOR
- Mus musculus
- Mtor
- Mus musculus
- Smg1
- Rattus norvegicus
- Mtor
- Schizosaccharomyces pombe
- tor2
External links
- Saccharomyces Genome Database
- Search
- Ensembl
- Search
- Entrez Gene
- ID 853529
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar