LongevityMap variant
Entry Details
- Longevity Association
- Significant
- Population
- Polish
- Study Design
- The -11377C > G, -11391G > A, and -11426A > G promoter polymorphisms of ADIPOQ were studied for association with longevity in 148 centenarians and 414 young controls
- Conclusions
- A very rare AA genotype of the -11391G > A polymorphism was significantly more common in centenarians than in young controls
- Identifier
- -11391G > A
- Cytogenetic Location
- 3q27.3
- UCSC Genome Browser
- View 3q27.3 on the UCSC genome browser
Gene details
- HGNC symbol
- ADIPOQ
- Aliases
- ACDC; ADPN; APM1; APM-1; GBP28; ACRP30; ADIPQTL1
- Common name
- adiponectin, C1Q and collagen domain containing
- Description
- This gene is expressed in adipose tissue exclusively. It encodes a protein with similarity to collagens X and VIII and complement factor C1q. The encoded protein circulates in the plasma and is involved with metabolic and hormonal processes. Mutations in this gene are associated with adiponectin deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Apr 2010]
- Other longevity studies of this gene
- 8
- OMIM
- 605441
- Ensembl
- ENSG00000181092
- UniProt/Swiss-Prot
- A8K660_HUMAN
- Entrez Gene
- 9370
- UniGene
- 80485
- HapMap
- View on HapMap