Mus musculusGenAge entry for Prop1 (Mus musculus)

Gene information (ID: 519)

Symbol
Prop1
Aliases
df; Prop-1
Name
Prophet of Pit1, paired-like homeodomain transcription factor
Organism
Mus musculus (AnAge)
Known functions and activities
Transcription factor involved in hormonal regulation and development

Potential relevance to longevity and/or ageing

Observations
Knockouts are dwarf but live approximately 1 year longer than controls.
Lifespan Effect
Increase
Genetic Manipulation
Knockout
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as PROP1
    GenDR gene manipulations
    • This gene is present as Prop1

    Homologs in other organisms

    Caenorhabditis elegans
    unc-42
    Drosophila melanogaster
    CG32532
    Homo sapiens
    PROP1
    Rattus norvegicus
    Prop1

    External links

    Mouse Genome Informatics
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (19127)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar