- Symbol
- MPT5
- Aliases
- HTR1; PUF5; UTH4
- Name
- Mpt5p
- Organism
- Saccharomyces cerevisiae (AnAge)
- Known functions and activities
- Binds to mRNAs encoding chromatin modifiers and spindle pole body components
- Observations
- Overexpression extended lifespan by about 25%.
- % change in avg or median lifespan
- Lifespan is about 25% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression
- Longevity Category
- Pro-Longevity
- Primary reference
-
- Observations
- Overexpression of MPT5 extends replicative life span by about 20%
- % change in avg or median lifespan
- Replicative lifespan is 20% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression
- Longevity Category
- Pro-Longevity
- Primary reference
-
- Observations
- Average chronological lifespan decreased by 50%. Rescued to the wt level by PKC1 overexpression
- % change in avg or median lifespan
- Replicative lifespan is 50% lower.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Deletion
- Longevity Category
- Necessary for fitness
- Primary reference
-
- Schizosaccharomyces pombe
- SPAC6G9.14
- Saccharomyces Genome Database
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (852697)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for MPT5 (Saccharomyces cerevisiae)