GenAge entry for HBP1 (Homo sapiens)

Gene name (HAGRID: 196)

HGNC symbol: HBP1
Aliases
Common name: HMG-box transcription factor 1

Potential relevance to the human ageing process

Main reason for selection: Entry selected based on evidence showing that the gene product to be a target of genes previously linked to ageing
Description: HBP1 has been related to DNA unwinding and stress response [860]. In mice, HBP1 and other HMG chromosomal proteins have been shown to suffer alterations at various levels during ageing [791], but HBP1 has not been directly related to human ageing.

Cytogenetic information

Cytogenetic band: 7q22-q31
Location: 107,169,015 bp to 107,202,529 bp
Orientation: Plus strand

Display region using the UCSC Genome Browser (GRCh38/hg38)

Protein information

Gene Ontology

Process:

GO:0006351; transcription, DNA-templated
GO:0006355; regulation of transcription, DNA-templated
GO:0007050; cell cycle arrest
GO:0016055; Wnt signaling pathway

Cellular component:

GO:0005654; nucleoplasm

Function:

GO:0003677; DNA binding
GO:0003723; RNA binding
GO:0005515; protein binding

Hide GO terms

Protein interactions and network

Protein-protein interacting partners in GenAge: MYC, CREBBP, EP300, RB1, HDAC1, SIN3A, ESR1
STRING interaction network

Retrieve sequences for HBP1

Promoter: Promoter
ORF: ORF
CDS: CDS

Homologs in model organisms

Danio rerio: hbp1
Mus musculus: Hbp1
Rattus norvegicus: Hbp1

In other databases

CellAge

This gene is present as HBP1