GenAge entry for Jund (Mus musculus)
Gene information (ID: 821)
- Symbol
- Jund
- Aliases
- Jund1
- Name
- Jun proto-oncogene related gene d
- Organism
- Mus musculus (AnAge)
Potential relevance to longevity and/or ageing
- Observations
- junD -/- mice exhibit features of premature aging (cataracts, slight hair loss, graying, varying degrees of cachexia, and lordokyphosis), and shortened lifespan. They also display persistent hypoglycemia due to enhanced insulin secretion. Mice also developed various types of neoplasia (most frequent cause of death being high-grade diffuse lymphomas) at similar frequency as in old WT mice.
- % change in max lifespan
- Maximum lifespan is 14% lower.
- % change in avg or median lifespan
- Average lifespan is 17% lower.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Knockout
- Longevity Category
- Pro-Longevity
- Primary reference
-
In other databases
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as JUND
Homologs in other organisms
External links
- Mouse Genome Informatics
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (16478)
- Homologues
- Search HomoloGene
- UniProt
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- Internet
- Search Google or Search Google Scholar