- Symbol
- Eps8
- Aliases
- AW261790
- Name
- Epidermal growth factor receptor pathway substrate 8
- Organism
- Mus musculus (AnAge)
- Observations
- Eps8 KO mice show a lean phenotype and increased lifespan. Mice appear to be caloric restricted, most probably due to an impaired fat absorption. Median survival of Eps8 KO mice was increased by 26%, mean survival by 37% and maximum survival by 9%. Lifespan was significantly extended both in male and female Eps8 KO mice.
- % change in max lifespan
- Maximum lifespan is 9% higher.
- % change in avg or median lifespan
- Median lifespan is 26% higher; Average lifespan is 37% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Deletion
- Longevity Category
- Anti-Longevity
- Primary reference
-
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as EPS8
- GenAge microarray genes
- A homolog of this gene for Homo sapiens is present as EPS8
- Caenorhabditis elegans
- eps-8
- Danio rerio
- eps8
- Drosophila melanogaster
- CG8907
- Drosophila melanogaster
- aru
- Homo sapiens
- EPS8
- Rattus norvegicus
- Eps8
- Mouse Genome Informatics
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (13860)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for Eps8 (Mus musculus)