LongevityMap variant
Entry Details
- Longevity Association
- Non-significant
- Population
- Italian
- Study Design
- G/A, codon 972 polymorphism was examined in healthy people 17-85 yr of age (n= 278; mean age, 54.8; 76 males and 202 females) and in healthy people 86-109 yr of age (n= 218; mean age, 98.0; 56 males and 162 females)
- Conclusions
- No significant differences relative to longevity were found
- Identifier
- IRS1
- In Other Studies (IDs)
- 167 183
- Cytogenetic Location
- 2q36.3
- UCSC Genome Browser
- View 2q36.3 on the UCSC genome browser
Gene details
- HGNC symbol
- IRS1
- Aliases
- HIRS-1
- Common name
- insulin receptor substrate 1
- Description
- This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. [provided by RefSeq, Nov 2009]
- Other longevity studies of this gene
- 5
- OMIM
- 147545
- Ensembl
- ENSG00000169047
- UniProt/Swiss-Prot
- A0A024R499_HUMAN
- Entrez Gene
- 3667
- UniGene
- 471508
- HapMap
- View on HapMap