GenAge entry for chico (Drosophila melanogaster)
Gene information (ID: 124)
- Symbol
- chico
- Aliases
- anon-WO0078940.1; anon-WO0078940.4; BcDNA.GH11263; Bc
- Name
- Insulin receptor substrate-1
- Organism
- Drosophila melanogaster (AnAge)
- Known functions and activities
- Insulin receptor substrate
Potential relevance to longevity and/or ageing
- Observations
- Lifespan extension of 48% in homozygotes and 36% in heterozygotes.
- % change in avg or median lifespan
- Lifespan is up to 48% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Knockout
- Longevity Category
- Anti-Longevity
- Primary reference
-
In other databases
- GenAge model organism genes
- GenAge human genes
- GenDR gene expression
- A homolog of this gene for Mus musculus is present as Irs2
- GenDR gene manipulations
- This gene is present as chico
- LongevityMap
Homologs in other organisms
- Danio rerio
- irs2b
- Danio rerio
- si:ch211-284e13.4
- Danio rerio
- irs2a
- Danio rerio
- irs1
- Danio rerio
- si:ch73-335l21.1
- Danio rerio
- irs4a
- Homo sapiens
- IRS4
- Homo sapiens
- IRS2
- Homo sapiens
- IRS1
- Mus musculus
- Irs2
- Mus musculus
- Irs1
- Mus musculus
- Irs3
- Mus musculus
- Irs4
- Rattus norvegicus
- Irs3
- Rattus norvegicus
- Irs2
- Rattus norvegicus
- Irs1
External links
- FlyBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (64880)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar