LongevityMap variant
Entry Details
- Longevity Association
- Non-significant
- Population
- Japanese
- Study Design
- 2 exonic polymorphisms were examined in 122 Japanese semisupercentenarians (older than 105, 107 female, 15 male, mean age 106.8 years) and 122 healthy younger controls (105 female, 17 male, mean age 33.33)
- Conclusions
- No significant differences relative to longevity were found
- Identifier
- IRS1
- In Other Studies (IDs)
- 120 183
- Cytogenetic Location
- 2q36.3
- UCSC Genome Browser
- View 2q36.3 on the UCSC genome browser
Gene details
- HGNC symbol
- IRS1
- Aliases
- HIRS-1
- Common name
- insulin receptor substrate 1
- Description
- This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. [provided by RefSeq, Nov 2009]
- Other longevity studies of this gene
- 5
- OMIM
- 147545
- Ensembl
- ENSG00000169047
- UniProt/Swiss-Prot
- A0A024R499_HUMAN
- Entrez Gene
- 3667
- UniGene
- 471508
- HapMap
- View on HapMap