- Symbol
- Sod
- Aliases
- CG11793; cSod; cSOD; Cu; Cu-Zn; SOD; Cu/Zn; sod; Cu/Zn; SOD
- Name
- Superoxide dismutase
- Organism
- Drosophila melanogaster (AnAge)
- Known functions and activities
- Antioxidant
- Observations
- Mutant flies displayed infertility and a reduction in lifespan.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Mutation
- Longevity Category
- Pro-Longevity
- Primary reference
-
- Observations
- Overexpression of catalase and Sod1 resulted in a one-third lifespan extension, a slower rate of mortality acceleration, and a delayed loss in physical performance.
- % change in avg or median lifespan
- Average lifespan is one-third higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression
- Longevity Category
- Pro-Longevity
- Primary reference
-
- Observations
- Cu/ZnSOD overexpression extended the mean lifespan by up to 48%. Simultaneous overexpression of catalase with Cu/ZnSOD had no added benefit, presumably due to a preexisting excess of catalase.
- % change in avg or median lifespan
- Average lifespan is up to 48% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression
- Longevity Category
- Pro-Longevity
- Primary reference
-
- GenAge model organism genes
- A homolog of this gene for Saccharomyces cerevisiae is present as SOD1
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as SOD1
- GenDR gene manipulations
- A homolog of this gene for Saccharomyces cerevisiae is present as SOD1
- LongevityMap
- A homolog of this gene for Homo sapiens is present as SOD1
- CellAge
- A homolog of this gene for Homo sapiens is present as SOD1
- Caenorhabditis elegans
- sod-4
- Danio rerio
- sod1
- Homo sapiens
- SOD1
- Mus musculus
- Sod1
- Rattus norvegicus
- Sod1
- Saccharomyces cerevisiae
- SOD1
- Schizosaccharomyces pombe
- sod1
- FlyBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (39251)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar