Drosophila melanogasterGenAge entry for Rpd3 (Drosophila melanogaster)

Gene information (ID: 556)

Symbol
Rpd3
Aliases
CG7471; dHDAC-1; dHDAC1; DHDAC1; Dmel\CG7471; dmHDA401;
Name
CG7471-PA
Organism
Drosophila melanogaster (AnAge)
Known functions and activities
Regulates transcription and silencing

Potential relevance to longevity and/or ageing

Observations
Mutations extend lifespan by 33% in males and 52% in females.
% change in avg or median lifespan
Female lifespan is 52% higher; Male lifespan is 33% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Saccharomyces cerevisiae is present as RPD3
    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as HDAC1
    • A homolog of this gene for Homo sapiens is present as HDAC2
    GenDR gene manipulations
    • This gene is present as Rpd3
    • A homolog of this gene for Saccharomyces cerevisiae is present as RPD3
    CellAge
    • A homolog of this gene for Homo sapiens is present as HDAC1
    • A homolog of this gene for Homo sapiens is present as HDAC2

    Homologs in other organisms

    Caenorhabditis elegans
    hda-1
    Caenorhabditis elegans
    hda-3
    Danio rerio
    hdac1
    Homo sapiens
    HDAC1
    Homo sapiens
    HDAC2
    Mus musculus
    Hdac1
    Mus musculus
    Hdac2
    Mus musculus
    Gm10093
    Rattus norvegicus
    Hdac2
    Rattus norvegicus
    Hdac1l
    Rattus norvegicus
    Hdac1
    Saccharomyces cerevisiae
    RPD3
    Schizosaccharomyces pombe
    clr6

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (38565)
    Homologues
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    UniProt
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    Internet
    Search Google or Search Google Scholar