GenAge entry for Xrcc6 (Mus musculus)
Gene information (ID: 736)
- Symbol
- Xrcc6
- Aliases
- Ku70; 70kDa; G22p1
- Name
- X-ray repair complementing defective repair in Chinese hamster cells 6
- Organism
- Mus musculus (AnAge)
- Known functions and activities
- The double strand break-repair protein
Potential relevance to longevity and/or ageing
- Observations
- XRCC5 and XRCC6 double knockout mice show decreased lifespan and signs of premature ageing without increase cancer incidence.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Knockout
- Longevity Category
- Pro-Longevity
- Primary reference
-
In other databases
- GenAge model organism genes
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as XRCC6
- LongevityMap
- A homolog of this gene for Homo sapiens is present as XRCC6
Homologs in other organisms
- Caenorhabditis elegans
- cku-70
- Danio rerio
- xrcc6
- Drosophila melanogaster
- Irbp
- Homo sapiens
- XRCC6
- Rattus norvegicus
- Xrcc6
- Saccharomyces cerevisiae
- YKU70
- Schizosaccharomyces pombe
- pku70
External links
- Mouse Genome Informatics
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (14375)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar