- Symbol
- Ghr
- Aliases
- GHBP; GHR/BP
- Name
- Growth hormone receptor
- Organism
- Mus musculus (AnAge)
- Known functions and activities
- Signal transduction of growth hormone
- Observations
- Knockouts are dwarf with significantly extended lifespan of up to 40% in males in the Ola-BALB/cJ background and 21% in females. In the C57Bl/6J background results are more modest but lifespan is still increased.
- % change in avg or median lifespan
- Lifespan is 21-40% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Knockout
- Longevity Category
- Anti-Longevity
- Primary reference
-
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as GHR
- GenDR gene expression
- This gene is present as Ghr
- GenDR gene manipulations
- This gene is present as Ghr
- LongevityMap
- A homolog of this gene for Homo sapiens is present as GHR
- Danio rerio
- ghra
- Danio rerio
- ghrb
- Homo sapiens
- GHR
- Rattus norvegicus
- Ghr
- Mouse Genome Informatics
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (14600)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for Ghr (Mus musculus)