Caenorhabditis elegansGenAge entry for eat-2 (Caenorhabditis elegans)

Gene information (ID: 204)

Symbol
eat-2
Name
EATing: abnormal pharyngeal pumping EAT-2
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Nicotinic Acetylcholine receptor Dalpha5 family member

Potential relevance to longevity and/or ageing

Observations
Mutations result in partial starvation by disrupting the function of the pharynx and an approximately 50% extension of lifespan.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenDR gene manipulations
    • This gene is present as eat-2

    Homologs in other organisms

    Danio rerio
    si:ch211-39a7.1
    Danio rerio
    si:ch73-380n15.2
    Danio rerio
    CABZ01069081.1
    Danio rerio
    chrna7
    Drosophila melanogaster
    nAChRalpha5
    Drosophila melanogaster
    nAChRalpha6
    Drosophila melanogaster
    nAChRalpha7
    Homo sapiens
    CHRFAM7A
    Homo sapiens
    CHRNA7
    Homo sapiens
    CHRNA7
    Mus musculus
    Chrna7
    Rattus norvegicus
    Chrna7

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (175072)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
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