GenAge entry for Eif5a2 (Mus musculus)
Gene information (ID: 1794)
- Symbol
- Eif5a2
- Aliases
- eIF5AII; 9630038B20
- Name
- eukaryotic translation initiation factor 5A2
- Organism
- Mus musculus (AnAge)
Potential relevance to longevity and/or ageing
- Observations
- Overexpression of Eif5a2 in mice results in accumulation of chromosomal instability and features resembling accelerated ageing, including a short lifespan (average lifespan of about 8 months), kyphosis, osteoporosis, delay of wound healing and ossification.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Overexpression
- Longevity Category
- Anti-Longevity
- Primary reference
-
In other databases
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as EIF5A2
Homologs in other organisms
- Danio rerio
- eif5a
- Drosophila melanogaster
- eIF-5A
- Homo sapiens
- EIF5A2
- Rattus norvegicus
- Eif5a2
- Saccharomyces cerevisiae
- HYP2
- Schizosaccharomyces pombe
- tif51b
External links
- Mouse Genome Informatics
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (208691)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar