Saccharomyces cerevisiaeGenAge entry for VPH1 (Saccharomyces cerevisiae)

Gene information (ID: 1719)

Symbol
VPH1
Name
Vacuolar pH
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
Replicative lifespan increased by 30% in the alpha strain
% change in avg or median lifespan
Replicative lifespan is 30% higher.
Lifespan Effect
Increase
Genetic Manipulation
Deletion
Longevity Category
Anti-Longevity
Primary reference
    Observations
    Replicative lifespan decreased by 15% in the a strain
    % change in avg or median lifespan
    Replicative lifespan is 15% lower.
    Lifespan Effect
    Decrease
    Genetic Manipulation
    Deletion
    Longevity Category
    Necessary for fitness
    Primary reference

      In other databases

      GenAge model organism genes
      • A homolog of this gene for Caenorhabditis elegans is present as unc-32
      • A homolog of this gene for Caenorhabditis elegans is present as vha-6
      CellAge
      • A homolog of this gene for Homo sapiens is present as ATP6V0A2
      CellAge gene expression
      • A homolog of this gene for Homo sapiens is present as ATP6V0A4

      Homologs in other organisms

      Caenorhabditis elegans
      vha-5
      Caenorhabditis elegans
      vha-7
      Caenorhabditis elegans
      unc-32
      Caenorhabditis elegans
      vha-6
      Danio rerio
      atp6v0a1a
      Danio rerio
      atp6v0a1b
      Danio rerio
      tcirg1b
      Danio rerio
      atp6v0a2b
      Danio rerio
      tcirg1a
      Danio rerio
      atp6v0a2a
      Danio rerio
      ATP6V0A4
      Drosophila melanogaster
      Vha100-3
      Drosophila melanogaster
      Vha100-1
      Drosophila melanogaster
      Vha100-5
      Drosophila melanogaster
      Vha100-4
      Drosophila melanogaster
      Vha100-2
      Homo sapiens
      TCIRG1
      Homo sapiens
      ATP6V0A4
      Homo sapiens
      ATP6V0A1
      Homo sapiens
      ATP6V0A2
      Mus musculus
      Atp6v0a1
      Mus musculus
      Tcirg1
      Mus musculus
      Atp6v0a4
      Mus musculus
      Atp6v0a2
      Rattus norvegicus
      Atp6v0a4
      Rattus norvegicus
      Atp6v0a1
      Rattus norvegicus
      Tctn2
      Rattus norvegicus
      Tcirg1
      Rattus norvegicus
      Tctn2

      External links

      Saccharomyces Genome Database
      Search
      Ensembl
      Search
      Entrez Gene
      View on Entrez Gene database (854444)
      Homologues
      Search HomoloGene
      UniProt
      Search
      Internet
      Search Google or Search Google Scholar