- Symbol
- Spargel
- Aliases
- CG; 9809; cg9809; CG9809; Dmel\CG9809; dPGC; dPGC-1; PGC-
- Name
- Spargel
- Organism
- Drosophila melanogaster (AnAge)
- Observations
- Tissue-specific overexpression of dPGC-1 in stem and progenitor cells within the digestive tract of female flies extends lifespan. Flies display a delay in the onset of aging-related changes in the intestine, leading to improved tissue homeostasis in old flies.
- % change in max lifespan
- Maximum female lifespan is up to 37% higher.
- % change in avg or median lifespan
- Median female lifespan is up to 33% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression in stem and progenitor cells
- Longevity Category
- Pro-Longevity
- Primary reference
-
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as PPARGC1A
- GenAge microarray genes
- A homolog of this gene for Homo sapiens is present as PPARGC1A
- LongevityMap
- A homolog of this gene for Homo sapiens is present as PPARGC1A
- CellAge
- A homolog of this gene for Homo sapiens is present as PPARGC1A
- Danio rerio
- ppargc1a
- Danio rerio
- ppargc1b
- Danio rerio
- si:dkey-93h22.8
- Danio rerio
- pprc1
- Homo sapiens
- PPRC1
- Homo sapiens
- PPARGC1A
- Homo sapiens
- PPARGC1B
- Mus musculus
- Pprc1
- Mus musculus
- Ppargc1b
- Mus musculus
- Ppargc1a
- Rattus norvegicus
- Pprc1
- Rattus norvegicus
- Ppargc1b
- Rattus norvegicus
- Ppargc1a
- FlyBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (40562)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for Spargel (Drosophila melanogaster)