- Symbol
- RpIIIC53
- Name
- RNA polymerase III subunit C53
- Organism
- Drosophila melanogaster (AnAge)
- Observations
- Flies with a heterozygous mutation in CG5147 (a subunit of Pol III) demonstrated an 11% increase in median lifespan. Homozygous mutants weren't viable. Gut specific inhibition of CG5147 also increased lifespan in females.
- % change in avg or median lifespan
- Median lifespan is 11% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Mutation
- Longevity Category
- Anti-Longevity
- Primary reference
-
- Danio rerio
- polr3d
- Danio rerio
- zgc:171971
- Homo sapiens
- POLR3D
- Mus musculus
- Polr3d
- Rattus norvegicus
- Polr3d
- FlyBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (40002)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for RpIIIC53 (Drosophila melanogaster)