- Symbol
- GLaz
- Aliases
- CG4604; DGLaz; Dmel\CG4604
- Name
- Glial Lazarillo
- Organism
- Drosophila melanogaster (AnAge)
- Known functions and activities
- Carrier of hydrophobic substances
- Observations
- Overexpression resulted in increased resistance to hyperoxia and a 29% extension of mean lifespan under normoxia. Lifespan was also extended 30-60% under starvation.
- % change in avg or median lifespan
- Average lifespan is 29% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression
- Longevity Category
- Pro-Longevity
- Primary reference
-
- Observations
- The absence of GLaz reduces the organism's resistance to oxidative stress and starvation and shortens male lifespan. Median survival time is reduced by 19.3%, maximum survival time is reduced by 10.9%.
- % change in max lifespan
- Maximum lifespan is 10.9% lower.
- % change in avg or median lifespan
- Median lifespan is 19.3% lower.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Deletion
- Longevity Category
- Pro-Longevity
- Primary reference
-
- GenAge microarray genes
- A homolog of this gene for Homo sapiens is present as APOD
- Danio rerio
- apoda.2
- Danio rerio
- apoda.1
- Danio rerio
- apodb
- Homo sapiens
- APOD
- Mus musculus
- Apod
- Rattus norvegicus
- Apod
- FlyBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (36447)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for GLaz (Drosophila melanogaster)