Drosophila melanogasterGenAge entry for EcR (Drosophila melanogaster)

Gene information (ID: 207)

Symbol
EcR
Aliases
anon-WO0229075.1; CG1765; CG8347; dECR; DEcR; Dhr23; dmE
Name
Ecdysone receptor
Organism
Drosophila melanogaster (AnAge)
Known functions and activities
Ecdysteroid hormone receptor activity

Potential relevance to longevity and/or ageing

Observations
Ecdysone receptor mutant heterozygotes live 40%-50% longer than controls.
% change in avg or median lifespan
Lifespan is 40-50% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    CellAge
    • A homolog of this gene for Homo sapiens is present as NR1H2

    Homologs in other organisms

    Danio rerio
    nr1h5
    Danio rerio
    nr1h3
    Danio rerio
    nr1h4
    Homo sapiens
    NR1H3
    Homo sapiens
    NR1H2
    Homo sapiens
    NR1H4
    Mus musculus
    Nr1h2
    Mus musculus
    Nr1h5
    Mus musculus
    Nr1h4
    Mus musculus
    Nr1h3
    Rattus norvegicus
    Nr1h5
    Rattus norvegicus
    Nr1h2
    Rattus norvegicus
    Nr1h3
    Rattus norvegicus
    Nr1h4

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (35540)
    Homologues
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    UniProt
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    Internet
    Search Google or Search Google Scholar