Drosophila melanogasterGenAge entry for Cct1 (Drosophila melanogaster)

Gene information (ID: 101)

Symbol
Cct1
Aliases
Cct; cct1; CCT1; CG1049; CT41283; Dmel\CG1049
Name
CTP:phosphocholine cytidylyltransferase 1
Organism
Drosophila melanogaster (AnAge)
Known functions and activities
Catalyzes the conversion of phosphocholine to CDP-choline

Potential relevance to longevity and/or ageing

Observations
Overexpression results in a 6-8% increase in mean lifespan.
% change in avg or median lifespan
Average lifespan is 6-8% higher.
Lifespan Effect
Increase
Genetic Manipulation
Overexpression
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    Caenorhabditis elegans
    F28A10.10
    Caenorhabditis elegans
    pcyt-1
    Caenorhabditis elegans
    Y18H1A.11
    Danio rerio
    pcyt1ab
    Danio rerio
    pcyt1ba
    Danio rerio
    pcyt1aa
    Danio rerio
    pcyt1bb
    Homo sapiens
    PCYT1A
    Homo sapiens
    PCYT1B
    Mus musculus
    Pcyt1b
    Mus musculus
    Pcyt1a
    Rattus norvegicus
    Pcyt1a
    Rattus norvegicus
    Pcyt1b
    Saccharomyces cerevisiae
    PCT1

    External links

    FlyBase
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    Entrez Gene
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    Homologues
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    UniProt
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    Internet
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