Saccharomyces cerevisiae GenDR Dietary Restriction Gene Manipulation: IRE1

Gene Information (Entrez Gene ID: 856478)

Symbol
IRE1
Aliases
ERN1
Name
bifunctional endoribonuclease/protein kinase IRE1
Organism
Saccharomyces cerevisiae (AnAge)
Entrez Gene ID
856478

Potential relevance to dietary restriction and ageing

Observations

Yeast cells were subjected to dietary restriction (0.05% glucose compared to 2% glucose as a control). Deletion of IRE1 resulted in a 11% decrease in mean replicative lifespan compared to the control.

References

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Caenorhabditis elegans is present as ire-1
    • A homolog of this gene for Drosophila melanogaster is present as Ire1
    GenDR gene manipulations
    • A homolog of this gene for Drosophila melanogaster is present as Ire1
    • A homolog of this gene for Caenorhabditis elegans is present as ire-1

    Homologs

    Caenorhabditis elegans
    zyg-1
    Caenorhabditis elegans
    ire-1
    Danio rerio
    CABZ01074298.1
    Danio rerio
    FO818712.1
    Danio rerio
    ern2
    Danio rerio
    ern1
    Drosophila melanogaster
    CG10177
    Drosophila melanogaster
    Ire1
    Homo sapiens
    ERN2
    Homo sapiens
    ERN1
    Mus musculus
    Ern1
    Mus musculus
    Ern2
    Rattus norvegicus
    Ern2
    Rattus norvegicus
    Ern1
    Schizosaccharomyces pombe
    ppk4

    External links

    Saccharomyces Genome Database
    Search
    Ensembl
    Search
    Entrez Gene
    ID 856478
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar