LongevityMap Gene
Gene details
- HGNC symbol
- REM2
- Aliases
- Common name
- RRAD and GEM like GTPase 2
- Description
- Cytogenetic Location
- 14q11.2
- UCSC Genome Browser
- View 14q11.2 on the UCSC genome browser
- OMIM
- 616955
- Ensembl
- ENSG00000139890
- UniProt/Swiss-Prot
- REM2_HUMAN
- Entrez Gene
- 161253
- UniGene
- 444911
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
- Caenorhabditis elegans
- Y52B11A.4
- Danio rerio
- rem2
- Drosophila melanogaster
- Rgk1
- Drosophila melanogaster
- Rgk3
- Drosophila melanogaster
- Rgk2
- Drosophila melanogaster
- CG42541
- Mus musculus
- Rem2
- Rattus norvegicus
- Rem2
- Saccharomyces cerevisiae
- RAS2
- Saccharomyces cerevisiae
- RAS1
In other databases
- GenAge model organism genes
Studies (1)
Significant/Non-significant: 0/1
- Longevity Association
- Non-significant
- Population
- Caucasians
- Study Design
- Meta-analysis of GWAS in Caucasians from four prospective cohort studies: the Age, Gene/Environment Susceptibility-Reykjavik Study, the Cardiovascular Health Study, the Framingham Heart Study, and the Rotterdam Study participating in the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium. Longevity was defined as survival to age 90 years or older (n = 1,836); the comparison group comprised cohort members who died between the ages of 55 and 80 years (n = 1,955).
- Conclusions
- There were 273 single-nucleotide polymorphism (SNP) associations with p < .0001, but none reached significance after correcting for multiple testing
- Indentifier
- rs12891954
- Reference