LongevityMap Gene
Gene details
- HGNC symbol
- LMO4
- Aliases
- Common name
- LIM domain only 4
- Description
- This gene encodes a cysteine-rich protein that contains two LIM domains but lacks a DNA-binding homeodomain. The encoded protein may play a role as a transcriptional regulator or as an oncogene. [provided by RefSeq, Aug 2008]
- Cytogenetic Location
- 1p22.3
- UCSC Genome Browser
- View 1p22.3 on the UCSC genome browser
- OMIM
- 603129
- Ensembl
- ENSG00000143013
- UniProt/Swiss-Prot
- LMO4_HUMAN
- Entrez Gene
- 8543
- UniGene
- 436792
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
Studies (1)
Significant/Non-significant: 0/1
- Longevity Association
- Non-significant
- Population
- European
- Study Design
- Meta-analysis of genome-wide association studies of survival and survival free of major disease or death. In total, there were 25,007 participants over 55 years of age and followed-up for over 10 years for mortality and over 8 years for event-free survival.
- Conclusions
- No SNP was significantly associated with mortality after correcting for multiple testing, but 14 independent SNPs were associated with time to death at a suggestive threshold
- Indentifier
- rs11582903
- Reference