LongevityMap Gene

Gene details

HGNC symbol
LINC02227 
Aliases
 
Common name
long intergenic non-protein coding RNA 2227 
Description
Cytogenetic Location
5q33.3
UCSC Genome Browser
View 5q33.3 on the UCSC genome browser
OMIM
Ensembl
ENSG00000276778
UniProt/Swiss-Prot
Entrez Gene
101927697
UniGene
483960
1000 Genomes
1000 Genomes

Homologs in model organisms

No homologs found

Studies (1)

Significant/Non-significant: 1/0

Longevity Association
Significant
Population
European
Study Design
A genome-wide association meta-analysis was performed in 7729 long-lived individuals of European descent (>=85 years) and 16,121 younger controls ( <65 years) followed by replication in an additional set of 13,060 long-lived individuals and 61 156 controls.
Conclusions
rs2149954 and rs4420638 were observed significantly associated with longevity. Meta-analysis showed rs2149954 (T) associates with increased survival.
Indentifier
rs2149954
Reference