LongevityMap Gene
Gene details
- HGNC symbol
- BIN2
- Aliases
- BRAP-1
- Common name
- bridging integrator 2
- Description
- Cytogenetic Location
- 12q13.13
- UCSC Genome Browser
- View 12q13.13 on the UCSC genome browser
- OMIM
- 605936
- Ensembl
- ENSG00000110934
- UniProt/Swiss-Prot
- A0A087X188_HUMAN
- Entrez Gene
- 51411
- UniGene
- 14770
- 1000 Genomes
- 1000 Genomes
Homologs in model organisms
- Caenorhabditis elegans
- amph-1
- Danio rerio
- bin2b
- Drosophila melanogaster
- Amph
- Mus musculus
- Bin2
- Rattus norvegicus
- Bin2
In other databases
- GenAge microarray genes
- This gene is present as BIN2
Studies (1)
Significant/Non-significant: 0/1
- Longevity Association
- Non-significant
- Population
- European
- Study Design
- Meta-analysis of genome-wide association studies of survival and survival free of major disease or death. In total, there were 25,007 participants over 55 years of age and followed-up for over 10 years for mortality and over 8 years for event-free survival.
- Conclusions
- No SNP was significantly associated with mortality after correcting for multiple testing, but 14 independent SNPs were associated with time to death at a suggestive threshold
- Indentifier
- rs766903
- Reference