LongevityMap variant

Entry Details

Longevity Association: Non-significant
Population: German
Study Design: The FCGR2A-His131Arg polymorphism was analyzed in a group of 408 German centenarians and two samples of younger Germans aged 60-75 and 18-49 years
Conclusions: No statistically significant differences were observed between the three age groups

HGNC symbol: FCGR2A
Aliases: CD32; FCG2; FcGR; CD32A; CDw32; FCGR2; IGFR2; FCGR2A1
Common name: Fc fragment of IgG receptor IIa
Description: This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008]
OMIM: 146790
Ensembl: ENSG00000143226
UniProt/Swiss-Prot: FCG2A_HUMAN
Entrez Gene: 2212
UniGene: 352642
HapMap: View on HapMap

Flesch et al. (2006)