- Symbol
- egl-30
- Name
- EGg Laying defective
- Organism
- Caenorhabditis elegans (AnAge)
- Observations
- Egl-30 mutants (reduction-of-function) showed a 31% median lifespan extension (in the daf-16 background) and a 38% median lifespan extension (compared to wild type). Conversely, egl-30 (gain-of-function) constitutively active Gaq mutants were short-lived.
- % change in avg or median lifespan
- Median lifespan is 38% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Mutation
- Longevity Category
- Anti-Longevity
- Primary reference
-
- Observations
- 15% mean lifespan extension
- % change in avg or median lifespan
- Average lifespan is 15% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Mutation
- Longevity Category
- Anti-Longevity
- Primary reference
-
- GenAge model organism genes
- A homolog of this gene for Saccharomyces cerevisiae is present as GPA2
- GenDR gene manipulations
- A homolog of this gene for Saccharomyces cerevisiae is present as GPA2
- Danio rerio
- gnaq
- Danio rerio
- gna11b
- Danio rerio
- gna11a
- Drosophila melanogaster
- CG30054
- Drosophila melanogaster
- CG17760
- Drosophila melanogaster
- Galphaq
- Homo sapiens
- GNA11
- Homo sapiens
- GNAQ
- Mus musculus
- Gnaq
- Mus musculus
- Gna11
- Rattus norvegicus
- Gna11
- Rattus norvegicus
- Gnaq
- Saccharomyces cerevisiae
- GPA2
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (171751)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar