- Symbol
- Casp2
- Aliases
- ICH-1; Nedd2; Caspase-2
- Name
- caspase 2
- Organism
- Mus musculus (AnAge)
- Known functions and activities
- Apoptosis
- Observations
- Loss of caspase-2 resulted in a shortened (10%) maximum lifespan and in enhanced ageing-related traits such as impaired hair growth, increased bone loss, and reduced body fat content.
- % change in max lifespan
- Maximum lifespan is 10% lower.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Knockout
- Longevity Category
- Pro-Longevity
- Primary reference
-
- GenAge model organism genes
- A homolog of this gene for Caenorhabditis elegans is present as ced-3
- A homolog of this gene for Caenorhabditis elegans is present as csp-2
- CellAge
- A homolog of this gene for Homo sapiens is present as CASP2
- Caenorhabditis elegans
- csp-2
- Caenorhabditis elegans
- ced-3
- Caenorhabditis elegans
- csp-1
- Caenorhabditis elegans
- csp-3
- Danio rerio
- casp2
- Drosophila melanogaster
- Dronc
- Homo sapiens
- CASP2
- Rattus norvegicus
- Casp2
- Mouse Genome Informatics
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (12366)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for Casp2 (Mus musculus)