Caenorhabditis elegansGenAge entry for ogdh-1 (Caenorhabditis elegans)

Gene information (ID: 650)

Symbol
ogdh-1
Name
Protein OGDH-1
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
2-oxoglutarate dehydrogenase, TCA cycle

Potential relevance to longevity and/or ageing

Observations
RNA interference increased mean lifespan by 79%.
% change in avg or median lifespan
Average lifespan is 79% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Saccharomyces cerevisiae is present as KGD1
    • A homolog of this gene for Schizosaccharomyces pombe is present as SPBC3H7.03c
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as OGDH

    Homologs in other organisms

    Danio rerio
    ogdha
    Danio rerio
    OGDHL
    Danio rerio
    ogdhb
    Drosophila melanogaster
    CG33791
    Drosophila melanogaster
    Nc73EF
    Homo sapiens
    OGDHL
    Homo sapiens
    OGDH
    Mus musculus
    Ogdhl
    Mus musculus
    Ogdh
    Rattus norvegicus
    Ogdhl
    Rattus norvegicus
    LOC103693780
    Rattus norvegicus
    LOC103693780
    Saccharomyces cerevisiae
    KGD1
    Schizosaccharomyces pombe
    kgd1

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (177235)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar