Mus musculusGenAge entry for Slc25a4 (Mus musculus)

Gene information (ID: 615)

Symbol
Slc25a4
Aliases
Ant1; AU019225
Name
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4
Organism
Mus musculus (AnAge)
Known functions and activities
Involved in the exchange of ADP and ATP across the mitochondrial inner membrane

Potential relevance to longevity and/or ageing

Observations
Knockouts exhibited a shortened lifespan and increased hydrogen peroxide production and in some tissues.
Lifespan Effect
Decrease
Genetic Manipulation
Knockout
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Saccharomyces cerevisiae is present as AAC3
    • A homolog of this gene for Saccharomyces cerevisiae is present as PET9
    CellAge gene expression
    • A homolog of this gene for Homo sapiens is present as SLC25A4

    Homologs in other organisms

    Caenorhabditis elegans
    F25B4.7
    Caenorhabditis elegans
    R07E3.4
    Danio rerio
    slc25a4
    Drosophila melanogaster
    sesB
    Homo sapiens
    SLC25A4
    Rattus norvegicus
    Slc25a4
    Saccharomyces cerevisiae
    AAC1
    Saccharomyces cerevisiae
    AAC3
    Saccharomyces cerevisiae
    PET9

    External links

    Mouse Genome Informatics
    Search
    Ensembl
    Search
    Entrez Gene
    View on Entrez Gene database (11739)
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar