Mus musculusGenAge entry for Prdx1 (Mus musculus)

Gene information (ID: 518)

Symbol
Prdx1
Aliases
PAG; OSF3; Paga; PrxI; TDX2; TPxA; prx1; MSP23; NkefA; OSF-
Name
Peroxiredoxin 1
Organism
Mus musculus (AnAge)
Known functions and activities
Involved in redox regulation

Potential relevance to longevity and/or ageing

Observations
Knockout mice have a shortened lifespan and develop severe haemolytic anaemia and several malignant cancers.
Lifespan Effect
Decrease
Genetic Manipulation
Knockout
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Caenorhabditis elegans is present as prdx-2
    • A homolog of this gene for Drosophila melanogaster is present as Jafrac1
    • A homolog of this gene for Saccharomyces cerevisiae is present as TSA1
    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as PRDX1
    GenDR gene manipulations
    • A homolog of this gene for Saccharomyces cerevisiae is present as TSA1

    Homologs in other organisms

    Caenorhabditis elegans
    prdx-2
    Danio rerio
    prdx1
    Drosophila melanogaster
    Jafrac1
    Drosophila melanogaster
    CG6888
    Homo sapiens
    PRDX1
    Rattus norvegicus
    Prdx1
    Rattus norvegicus
    AABR07012795.1
    Saccharomyces cerevisiae
    TSA1
    Saccharomyces cerevisiae
    TSA2

    External links

    Mouse Genome Informatics
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (18477)
    Homologues
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    UniProt
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    Internet
    Search Google or Search Google Scholar