- Symbol
- Pou1f1
- Aliases
- dw; Hmp1; Pit1; GHF-1; Pit-1; dwarf; Pit1-rs1
- Name
- POU domain, class 1, transcription factor 1
- Organism
- Mus musculus (AnAge)
- Known functions and activities
- Transcription factor that regulates pituitary development
- Observations
- Deletion resulted in more than 40% increase in mean and maximal longevity on the relatively long-lived (C3H/HeJ x DW/J)F(1) background.
- % change in max lifespan
- Maximum lifespan is more than 40% higher.
- % change in avg or median lifespan
- Average lifespan is more than 40% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Deletion
- Longevity Category
- Anti-Longevity
- Primary reference
-
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as POU1F1
- Danio rerio
- pou1f1
- Homo sapiens
- POU1F1
- Rattus norvegicus
- Pou1f1
- Mouse Genome Informatics
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (18736)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for Pou1f1 (Mus musculus)