- Symbol
- Pck1
- Aliases
- PEPCK; Pck-1; AI265463
- Name
- phosphoenolpyruvate carboxykinase 1, cytosolic
- Organism
- Mus musculus (AnAge)
- Observations
- Overexpression in skeletal muscle results in an increased number of mitochondria and extended lifespan. Transgenic mice ate 60% more than controls but had half the body weight and 10% of the body fat.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression
- Longevity Category
- Pro-Longevity
- Primary reference
-
- GenAge model organism genes
- A homolog of this gene for Caenorhabditis elegans is present as pck-2
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as PCK1
- GenDR gene manipulations
- This gene is present as Pck1
- Caenorhabditis elegans
- pck-3
- Caenorhabditis elegans
- pck-1
- Caenorhabditis elegans
- pck-2
- Danio rerio
- pck1
- Drosophila melanogaster
- CG10924
- Drosophila melanogaster
- Pepck
- Homo sapiens
- PCK1
- Rattus norvegicus
- Pck1
- Mouse Genome Informatics
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (18534)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for Pck1 (Mus musculus)