- Symbol
- par-5
- Name
- abnormal embryonic PARtitioning of cytoplasm
- Organism
- Caenorhabditis elegans (AnAge)
- Observations
- RNA interference slightly shortens lifespan and suppresses life-extension by sir-2.1 overexpression but not by daf-2 mutants. Overexpression extends lifespan by 30%, but is suppressed by RNA interference of daf-16.
- % change in avg or median lifespan
- Lifespan is 30% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression
- Longevity Category
- Pro-Longevity
- Primary reference
-
- Observations
- Post developmental RNAi let to a 15% mean lifespan reduction in wild type though no significant changes in maximal lifespan.
- % change in avg or median lifespan
- Average lifespan is 15% lower.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- RNA interference
- Longevity Category
- Pro-Longevity
- Primary reference
-
- GenAge model organism genes
- A homolog of this gene for Saccharomyces cerevisiae is present as BMH1
- A homolog of this gene for Saccharomyces cerevisiae is present as BMH2
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as YWHAZ
- LongevityMap
- A homolog of this gene for Homo sapiens is present as YWHAG
- CellAge
- A homolog of this gene for Homo sapiens is present as SFN
- A homolog of this gene for Homo sapiens is present as YWHAB
- A homolog of this gene for Homo sapiens is present as YWHAZ
- Danio rerio
- ywhaqa
- Danio rerio
- ywhabb
- Danio rerio
- ywhaz
- Danio rerio
- ywhaqb
- Danio rerio
- ywhabl
- Danio rerio
- ywhaba
- Danio rerio
- ywhag1
- Danio rerio
- ywhah
- Danio rerio
- ywhag2
- Drosophila melanogaster
- 14-3-3zeta
- Homo sapiens
- SFN
- Homo sapiens
- YWHAB
- Homo sapiens
- YWHAH
- Homo sapiens
- YWHAQ
- Homo sapiens
- YWHAZ
- Homo sapiens
- YWHAG
- Mus musculus
- Sfn
- Mus musculus
- Ywhah
- Mus musculus
- Ywhag
- Mus musculus
- Ywhaq
- Mus musculus
- Ywhaz
- Mus musculus
- Ywhab
- Rattus norvegicus
- Ywhaz
- Rattus norvegicus
- Sfn
- Rattus norvegicus
- LOC298795
- Rattus norvegicus
- Ywhag
- Rattus norvegicus
- Ywhab
- Rattus norvegicus
- Ywhaq
- Rattus norvegicus
- Ywhah
- Saccharomyces cerevisiae
- BMH2
- Saccharomyces cerevisiae
- BMH1
- Schizosaccharomyces pombe
- rad25
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (178113)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for par-5 (Caenorhabditis elegans)