GenAge entry for MEC1 (Saccharomyces cerevisiae)
Gene information (ID: 430)
- Symbol
- MEC1
- Aliases
- ESR1; RAD31; SAD3
- Name
- Mec1p
- Organism
- Saccharomyces cerevisiae (AnAge)
- Known functions and activities
- Involved in replication stress and DNA damage
Potential relevance to longevity and/or ageing
- Observations
- Mutants have a 3-fold reduced mean and maximum chronological lifespan under conditions of medium depletion.
- % change in avg or median lifespan
- Lifespan is three-fold lower.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Mutation
- Longevity Category
- Necessary for fitness
- Primary reference
-
In other databases
- GenAge model organism genes
- A homolog of this gene for Mus musculus is present as Atr
- GenAge human genes
- LongevityMap
- CellAge
Homologs in other organisms
- Caenorhabditis elegans
- atl-1
- Danio rerio
- prkdc
- Danio rerio
- atr
- Drosophila melanogaster
- mei-41
- Homo sapiens
- ATR
- Homo sapiens
- PRKDC
- Mus musculus
- Atr
- Mus musculus
- Prkdc
- Rattus norvegicus
- Prkdc
- Rattus norvegicus
- Atr
- Schizosaccharomyces pombe
- rad3
External links
- Saccharomyces Genome Database
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (852433)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar