- Symbol
- InR
- Aliases
- 18402; CG18402; DIHR; DILR; dinr; dInr; dInR; dINR; DInr; D
- Name
- Insulin-like 1 receptor
- Organism
- Drosophila melanogaster (AnAge)
- Known functions and activities
- InR regulates cell growth and proliferation through the dP13K/dAkt pathway
- Observations
- Mutations result in dwarf females with extended lifespan of up to 85% and dwarf males with reduced late age-specific mortality.
- % change in avg or median lifespan
- Average female lifespan is up to 85% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Mutation
- Longevity Category
- Anti-Longevity
- Primary reference
-
- GenAge model organism genes
- A homolog of this gene for Caenorhabditis elegans is present as daf-2
- A homolog of this gene for Mus musculus is present as Igf1r
- A homolog of this gene for Mus musculus is present as Insr
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as IGF1R
- A homolog of this gene for Homo sapiens is present as INSR
- GenDR gene manipulations
- This gene is present as InR
- A homolog of this gene for Caenorhabditis elegans is present as daf-2
- LongevityMap
- A homolog of this gene for Homo sapiens is present as IGF1R
- A homolog of this gene for Homo sapiens is present as INSR
- Caenorhabditis elegans
- daf-2
- Danio rerio
- igf1rb
- Danio rerio
- insrb
- Danio rerio
- insra
- Danio rerio
- igf1ra
- Homo sapiens
- INSRR
- Homo sapiens
- IGF1R
- Homo sapiens
- INSR
- Mus musculus
- Insrr
- Mus musculus
- Igf1r
- Mus musculus
- Insr
- Rattus norvegicus
- Insrr
- Rattus norvegicus
- Insr
- Rattus norvegicus
- Igf1r
- FlyBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (42549)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for InR (Drosophila melanogaster)