Drosophila melanogasterGenAge entry for Hsp27 (Drosophila melanogaster)

Gene information (ID: 350)

Symbol
Hsp27
Aliases
27; 27K; 28; anon-WO0140519.69; CG4466; Dhsp27; Dmel\CG4
Name
Heat shock protein 27
Organism
Drosophila melanogaster (AnAge)
Known functions and activities
Heat shock response

Potential relevance to longevity and/or ageing

Observations
Overexpression increased stress resistance and extended the mean lifespan by 30%.
% change in avg or median lifespan
Average lifespan is 30% higher.
Lifespan Effect
Increase
Genetic Manipulation
Overexpression
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Caenorhabditis elegans is present as hsp-16.1
    • A homolog of this gene for Caenorhabditis elegans is present as hsp-16.48
    • A homolog of this gene for Caenorhabditis elegans is present as hsp-16.49
    • A homolog of this gene for Caenorhabditis elegans is present as sip-1
    GenAge microarray genes
    • A homolog of this gene for Homo sapiens is present as CRYAB
    CellAge gene expression
    • A homolog of this gene for Homo sapiens is present as CRYAB

    Homologs in other organisms

    Caenorhabditis elegans
    hsp-16.1
    Caenorhabditis elegans
    hsp-16.49
    Caenorhabditis elegans
    hsp-16.49
    Caenorhabditis elegans
    hsp-16.48
    Caenorhabditis elegans
    hsp-16.11
    Caenorhabditis elegans
    hsp-43
    Caenorhabditis elegans
    Y55F3BR.6
    Caenorhabditis elegans
    hsp-17
    Caenorhabditis elegans
    F08H9.4
    Caenorhabditis elegans
    F08H9.3
    Caenorhabditis elegans
    hsp-16.11
    Caenorhabditis elegans
    hsp-16.48
    Caenorhabditis elegans
    hsp-16.1
    Caenorhabditis elegans
    hsp-16.2
    Caenorhabditis elegans
    sip-1
    Caenorhabditis elegans
    hsp-16.41
    Danio rerio
    cryabb
    Danio rerio
    cryaa
    Danio rerio
    cryaba
    Danio rerio
    hspb6
    Homo sapiens
    CRYAB
    Homo sapiens
    102724652
    Homo sapiens
    HSPB6
    Homo sapiens
    CRYAA
    Mus musculus
    Hspb6
    Mus musculus
    Cryab
    Mus musculus
    Cryaa
    Rattus norvegicus
    Cryab
    Rattus norvegicus
    Hspb6
    Rattus norvegicus
    Cryaa

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (39078)
    Homologues
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    UniProt
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    Internet
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