Mus musculusGenAge entry for Akt1 (Mus musculus)

Gene information (ID: 1810)

Symbol
Akt1
Aliases
Akt; PKB; Rac; PKB/Akt; PKBalpha
Name
thymoma viral proto-oncogene 1
Organism
Mus musculus (AnAge)

Potential relevance to longevity and/or ageing

Observations
Haploinsufficient mice had a lower body weight and a longer lifespan. Mean lifespan was 8% longer in males and 15% longer in females when compared to wild-type.
% change in avg or median lifespan
Average lifespan is 11.5% higher.
Lifespan Effect
Increase
Genetic Manipulation
Genetic reduction
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Caenorhabditis elegans is present as akt-1
    • A homolog of this gene for Saccharomyces cerevisiae is present as SCH9
    • A homolog of this gene for Drosophila melanogaster is present as Akt1
    • A homolog of this gene for Saccharomyces cerevisiae is present as YPK1
    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as AKT1
    GenDR gene manipulations
    • A homolog of this gene for Saccharomyces cerevisiae is present as SCH9
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as AKT1
    CellAge
    • A homolog of this gene for Homo sapiens is present as AKT1

    Homologs in other organisms

    Caenorhabditis elegans
    akt-2
    Caenorhabditis elegans
    akt-1
    Danio rerio
    AKT1
    Drosophila melanogaster
    Akt1
    Homo sapiens
    AKT1
    Rattus norvegicus
    Akt1
    Saccharomyces cerevisiae
    SCH9
    Saccharomyces cerevisiae
    YPK2
    Saccharomyces cerevisiae
    YPK1

    External links

    Mouse Genome Informatics
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (11651)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar