Caenorhabditis elegansGenAge entry for vps-37 (Caenorhabditis elegans)

Gene information (ID: 102)

Symbol
vps-37
Name
related to yeast Vacuolar Protein Sorting factor
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
ESCRT-I subunit

Potential relevance to longevity and/or ageing

Observations
RNA interference decreased median lifespan by 44% in wild type animals, 47% in a daf-2 background and 33% in daf-2/daf-16 double mutants.
% change in avg or median lifespan
Median lifespan is 44% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    vps37b
    Danio rerio
    VPS37B (1 of many)
    Danio rerio
    si:ch211-284f22.3
    Danio rerio
    vps37a
    Danio rerio
    vps37c
    Drosophila melanogaster
    Vps37B
    Homo sapiens
    VPS37C
    Homo sapiens
    VPS37B
    Homo sapiens
    VPS37A
    Homo sapiens
    VPS37D
    Mus musculus
    Vps37b
    Mus musculus
    Vps37d
    Mus musculus
    Vps37c
    Mus musculus
    Vps37a
    Rattus norvegicus
    Vps37d
    Rattus norvegicus
    NEWGENE_1309258
    Rattus norvegicus
    Vps37c
    Rattus norvegicus
    Vps37c
    Rattus norvegicus
    Vps37b
    Rattus norvegicus
    Vps37a
    Rattus norvegicus
    NEWGENE_1309258

    External links

    WormBase
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    Entrez Gene
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    Homologues
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    UniProt
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    Internet
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