Caenorhabditis elegansGenAge entry for vps-36 (Caenorhabditis elegans)

Gene information (ID: 663)

Symbol
vps-36
Name
VPS-36
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Endosomal vesicular trafficking

Potential relevance to longevity and/or ageing

Observations
RNA interference decreased median lifespan by 27% in wild type animals, 27% in a daf-2 background and 9% in daf-2/daf-16 double mutants.
% change in avg or median lifespan
Median lifespan is 27% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge microarray genes
    • A homolog of this gene for Homo sapiens is present as VPS36

    Homologs in other organisms

    Danio rerio
    vps36
    Drosophila melanogaster
    Vps36
    Homo sapiens
    VPS36
    Mus musculus
    Vps36
    Rattus norvegicus
    Vps36
    Schizosaccharomyces pombe
    vps36

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (179520)
    Homologues
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    UniProt
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    Internet
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