Caenorhabditis elegansGenAge entry for vps-22 (Caenorhabditis elegans)

Gene information (ID: 68)

Symbol
vps-22
Name
Protein VPS-22
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Vps22p subunit of the ESCRT-II complex

Potential relevance to longevity and/or ageing

Observations
RNA interference decreased median lifespan by 43% in wild type animals, 33% in a daf-2 background and 9% in daf-2/daf-16 double mutants.
% change in avg or median lifespan
Median lifespan is 43% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    snf8
    Drosophila melanogaster
    lsn
    Homo sapiens
    SNF8
    Mus musculus
    Snf8
    Rattus norvegicus
    Snf8
    Saccharomyces cerevisiae
    SNF8
    Schizosaccharomyces pombe
    dot2

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (175672)
    Homologues
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    UniProt
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    Internet
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